Problems in Measurement of Myocardial Contractility
نویسندگان
چکیده
منابع مشابه
the effect of phenoxybenzamine on myocardial contractility in dogs
the cardiac action of phenoxybenzamine (dibenzyline) was studiedusing the maximum rate of pressure rise in the left ventricle as a measure of myocardial contractility. cardiac function was assessed by increasing the pressure load on the heart and measuring contractility as reflected by dp/dt. dibenzyline was found to change the cardiac response to pressure load. the rate of pressure increase in...
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The standard procedure for measuring left ventricular (LV) contractility is by use of a conductance catheter with which LV volume and LV pressure can be determined simultaneously. In 1973, Sagawa (1) was the first to use this catheter, which had been developed at the University Hospital Leiden, and he was able to show that an elastance curve can be determined from a series of loop diagrams whic...
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Background In aortic stenosis(AS) with normal left ventricular ejection fraction(LV EF), circumferential and longitudinal systolic strains(CSt, LSt) are reduced but the underlying mechanisms are uncertain. Conventional indices of afterload(A) per unit of myocardium are suboptimal for strain analysis and based on inaccurate assumptions about myocardial properties, while conventional contractilit...
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S100A1, a Ca(2+) binding protein of the EF-hand type, is preferentially expressed in myocardial tissue and has been found to colocalize with the sarcoplasmic reticulum (SR) and the contractile filaments in cardiac tissue. Because S100A1 is known to modulate SR Ca(2+) handling in skeletal muscle, we sought to investigate the specific role of S100A1 in the regulation of myocardial contractility. ...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1972
ISSN: 0035-9157
DOI: 10.1177/003591577206500620